Anatomy notes on dna and rna- very descriptive
Date Submitted: 12/17/2003 17:14:34
Anatomy-
-Diagram of Dna-
T-nucleobase not in Rna
Meischer- nucleic acid, 1st saw Dna, 1868
Pauling- Structure of Dna, triple strand.
Feulgen- staining dna, whre it is located.
Levene- Dna a contained A-G(purines) and T-C(pyrimidines). Sugar and phosphate present. Thought equal amounts present.
Chargaff- diff. Amounts of all four, t-a c-g
Watson/Crick- base of Rosalind Franklin, double coil helix.
Fanklin-xray crystallography findings. Noble peace award.
Okazaki-leading strand, lagging strand
Nirenberg/Khorana-64 codons
Collins-Human
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amino acids.
Rflps- normal- 5, 14, 10, 6, skin, cheek, saliva, hair, semen, white blood cells.
-<Tab/>sickle cell anemia, tay sachs, hemophilia, huntingtons, cystic fibrosis
autoradiograph-identify bases.
probe- sticks to gene.
Mitochondrial Dna- evoluntionary dna, found in mother egg.
Enzyme- speeds up chemical reaction
electrophorese-show how dna has been cute with restriction enzymes, determine the number of base pairs.
Human Genome project- 40,000, stopped in 2003, 1900-2005, francis collins. Venter- use of dna sequencing analyzers.
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