Hemophilia Manitoba
Hemophilia Manitoba
Hemophilia Manitoba, or hemophilia, is a sex-linked genetic 
disorder that is effecting about 20,000 Americans, most of 
which males. A person with hemophilia either has an 
inactive or inadequate supply of one of several blood 
factors needed for blood to clot. Because of this 
hemophilia can be mild, moderate, or severe. Severe 
hemophiliacs are at risk for bleeding during surgery, 
trauma, or even dental work. There are two types of 
hemophilia, A and B (
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times per 
million gametes produced. The causes for mutations are 
still poorly understood, but it is known that some high- 
energy chemical and nuclear radiation increases the rate of 
mutation. 
Bibliography 
Bornstein, Jerry and Sandy. What is Genetics? New York: 
Julian Messner, 1979.
Cartwright, Frederick F. Disease and History. New York: 
Dorset Press, 1991.
Zallen, Doris Teichler. Does It Run in the Family. New 
Brunswick: Rutgers University Press, 1997.
Wingerson, Lois. Mapping Our Genes. New York: Penguin 
Books, 1990
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